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To secure their fortune — and future — two ruthless siblings build a family dynasty that begins to crumble when their heirs mysteriously die, one by one. Ruthless siblings Roderick and Madeline Usher have built Fortunato Pharmaceuticals into an empire of wealth, privilege and power. But past secrets come to light when the heirs to the Usher dynasty start dying at the hands of a mysterious woman from their youth.
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But the themes remain the same—guilt, obsession, vengeance, and a supernatural sense of justice. Roderick Usher’s children are getting what they deserve, not merely because they are the fruit of a very poisoned tree but because they have made horrific decisions to stay in the shelter of wealth and privilege. It turns out that almost every branch of the Usher family tree has been cut by violent horror.
Mary McDonnell as Madeline Usher
In the Roger Corman film from 1960, released in the United States as House of Usher, Vincent Price starred as Roderick Usher, Myrna Fahey as Madeline and Mark Damon as Philip Winthrop, Madeline's fiancé. The film was Corman's first in a series of eight films inspired by the works of Edgar Allan Poe. Like Madeline, Roderick is connected to the mansion, the titular House of Usher.

‘The Fall of the House of Usher’ Cast Guide: Meet the Actors Behind Edgar Allan Poe’s Usher Family
Loosely based on various works by 19th-century author Edgar Allan Poe (most prominently the eponymous 1840 short story), the series adapts otherwise unrelated stories and characters by Poe into a single nonlinear narrative set from 1953 to 2023. It recounts both the rise to power of Roderick Usher, the powerful CEO of a corrupt pharmaceutical company and his sister Madeline Usher, the firm's genius COO, and the events leading to the deaths of all six of Roderick’s children. It stars an ensemble cast led by Carla Gugino as a mysterious woman plaguing the Ushers, Bruce Greenwood as an elderly Roderick and Mary McDonnell as an elderly Madeline. This modern take on the Edgar Allan Poe story of the same name transports fans into the world of the Usher family, led by sibling duo Roderick and Madeline. Together, the twins have headed Fortunato Pharmaceuticals, establishing an empire of wealth, privilege and power — but at a cost.
Throughout the tale and her varying states of consciousness, Madeline completely ignores the narrator's presence. After Roderick Usher claims that Madeline has died, the narrator helps Usher entomb Madeline in an underground vault despite noticing Madeline's flushed, lifelike appearance. A storm begins, and Roderick comes to the narrator's bedroom (which is situated directly above the house's vault) in an almost hysterical state. Throwing the windows open to the storm, Roderick points out that the lake surrounding the house seems to glow in the dark, just as Roderick depicted in his paintings, but there is no lightning or other explainable source of the glow.
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What’s more interesting is to watch how the fallout of their decisions fell on Roderick’s many children, all torn apart by some of Poe’s most memorable creations. English majors will likely know where some of the stories are going just by seeing the episode names. When the young and trendy Prospero Usher (Sauriyan Sapkota) decides to host an exclusive sex-and-drugs party at one of dad’s old factories in an abbey, readers of The Masque of the Red Death will know it’s going to be a gruesome scene. However, Flanagan is smart enough to shift the Poe narratives ever so slightly for a modern audience. His version of The Tell-Tale Heart is a modern gem, and “The Gold-Bug” is reimagined as a new brand for the Usher company.
Further, Roderick believes that his fate is connected to the family mansion. The House of Usher is a 2006 American drama thriller film based on the 1839 Edgar Allan Poe short story "The Fall of the House of Usher". Philip Winthrop (Mark Damon) travels to the House of Usher, a desolate mansion surrounded by a murky swamp, to see his fiancée Madeline Usher (Myrna Fahey). Roderick foresees the family evils being propagated into future generations with a marriage to Madeline and vehemently discourages the union. Philip becomes increasingly desperate to take Madeline away; desperate to get away from her brother, she agrees to leave with him. House of Usher will put a new twist on the short horror story by writer Edgar Allen Poe.
Roderick Usher (Bruce Greenwood) attends a joint funeral for a number of his adult children, and in a montage of press coverage, we see how a series of “freak accidents” has wiped out his entire bloodline. The Usher patriarch then sits in a dilapidated mansion with Carl Lumbly’s Auguste Dupin (based on Poe’s famous recurring character who is considered the first detective in fiction) and offers him a confession. We then flash back a few weeks to when the Usher clan were on top of the world, having become Sackler-esque billionaires peddling opiates that have inflicted untold misery on the American public, and begin to watch their painful demise. As Flanagan’s IMDB page grows, so does the Flanaverse, and the new Netflix’s series “Usher” is assembling what could be the biggest cast of Flanagan favorites of all time.
A second silent film version, also released in 1928, was directed by James Sibley Watson and Melville Webber. La Chute de la maison Usher is a 1928 silent French horror film directed by Jean Epstein starring Marguerite Gance, Jean Debucourt, and Charles Lamy. Flanagan finishes his Netflix contract on a high, gleefully capturing Poe’s magic, eerie romance and sense of dread. His shows have become the streaming service’s best offerings for spooky season, and it is hard to imagine how that void will be filled. It’s not perfect – the order in which the Poe family meet their fates is a case of diminishing returns, as its most intriguing members are dispatched too quickly.
In 1950, a British film version of The Fall of the House of Usher was produced starring Gwen Watford, Kay Tendeter and Irving Steen.
House of Usher (also known as The Fall of the House of Usher) is a 1960 American gothic horror film directed by Roger Corman and written by Richard Matheson from the 1839 short story "The Fall of the House of Usher" by Edgar Allan Poe. The film was the first of eight Corman/Poe feature films and stars Vincent Price, Myrna Fahey, Mark Damon and Harry Ellerbe. Usher has been reimagined as the head of a massive pharmaceutical company he runs with his twin sister, Madeline (Mary McDonnell).
As a parent himself, Roderick doesn’t fare much better, having six children by five different women who range from obnoxious hedonists (Napoleon and Prospero Usher) to despicable creeps (Frederick, Tamerlane and Victoria) to obnoxious, despicable hedonist creeps (Camille). The family is made up of Flanagan’s regular ensemble of actors, and to buy them as relatives requires a lot of suspension of disbelief, but for Flanagan fans, there’s great fun to be had seeing how these favourites fit into his new tale of terror. Ruth Codd (the highlight of The Midnight Club) plays Roderick’s much younger wife Juno, a former heroin addict whose life was turned around thanks to the drugs the Ushers peddle, while Rahul Kohli, Henry Thomas and Kate Siegel each take on a dastardly member of the Usher brood.
It is revealed that Roderick's sister, Madeline, is also ill and falls into cataleptic, deathlike trances. Meanwhile, Jill becomes intimate with Rick and tells him she has missed her period. In the meantime, Jill has discovered that the Usher family has practiced twincest for the past five or six generations, right down to Maddy and Rick. All the prior generations had twins, who later became a couple and birthed twins of their own and so on down the line to Maddy and Rick, who were to continue the Usher curse. After the main cast of Mike Flanagan and Trevor Macy’s The Fall of the House of Usher was released on Thursday, Netflix has announced the full lineup of stars that will be joining Mark Hamill, Carla Gugino, Carl Lumbly, and more in the upcoming miniseries. From his arrival, the narrator notes the family's isolationist tendencies, as well as the cryptic and special connection between Madeline and Roderick, the final living members of the Usher family.
Late one stormy night, Roderick Usher (Bruce Greenwood) invites an investigator named C. He offers to lay out the truth about his family’s criminal, violent history. All of these nightmarish visions are attached to the family drama that Usher offers up for Dupin, giving the season a clever episodic structure in that each chapter intertwines a different Poe source into the overall saga of the Ushers. The narrator and Roderick place her in a tomb despite her flushed, lively appearance.
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